CBLs technology:

CBL produces complex peptides utilizing CBL developed technology. The in-house developed technology mitigates outside patent issues and allows CBL to produce to the highest quality standards. Some of the relevant patents are the following:

May 19, 2010

Applicant: Chemical & Biopharmaceutical Laboratories of Patras SA Short Title: Relaxin Peptide Synthesis

Inventors: Kleomenis K Barlos, Kostas K Barlos, Dimitrios Gatos

(International filing date 19 May 2010; WO 2010/140060; claiming priority from GR Application no. 20090100310, dated 1 June 2009)

May 19, 2010

October 8, 2010

Applicant: Chemical & Biopharmaceutical Laboratories of Patras SA Short Title: Insulin Like Peptides

Inventors: Kleomenis Barlos, Konstantinos Barlos

(International filing date 8 October 2010; WO 2011/042762; claiming priority from GR Application no. 20090100545, dated 8 October 2009)

October 8, 2010

February 26, 2013

Applicant: CBL Patras S.A.

Short Title: Peptide Synthesis Via Side Chain Attachment Inventors: Kleomenis Barlos

(International filing date 26 February 2013; WO 2013/098802; claiming priority from US Provisional application no. 61/581,503, dated 29 December 2011

February 26, 2013

April 19, 2013

Applicant:  CBL Patras

Short Title:  Insulin Synthesis

Inventors:  Kleomenis Barlos, Konstantinos Barlos, Dimitrios Gatos, Michail Ziovas, Efstathios Liopyris

(International filing date 19 April 2013; WO 2013/156977; claiming priority from US Provisional application no. 61/636,193, dated 20 April 2012)

April 19, 2013

June 19, 2014

Applicant: Chemical & Biopharmaceutical Laboratories of Patras SA

Short Title:  Peptide Resin Conjugate and Use Thereof

Inventors:  Kleomenis Barlos, Kostas Barlos, Dimitrios Gatos

(International filing date 19 June 2014; WO 2014/203193; claiming priority from UK application no. 1310921.0 dated 19 June 2013)

June 19, 2014

August 28, 2014

Applicant:  Chemical & Biopharmaceutical Laboratories of Patras SA

Short title:  Amino Diacids Containing Peptide Modifiers

Inventors:  Kleomenis Barlos, Dimitrios Gatos, Kostas Barlos, Zoi Vasileiou

(International filing date 28 August 2014; WO 2015/028966; claiming priority from UK application no. 1315335.8 dated 29 August 2013)

August 28, 2014

December 4, 2014

Applicant:  Chemical & Biopharmaceutical Laboratories of Patras SA

Short Title:  Biologically Active Insulin Derivatives

Inventors:  Kleomenis Barlos, Dimitrios Gatos, Kostas Barlos, Michail Ziovas

(International filing date 4 December 2014; WO 2015/083114; claiming priority from UK application no. 1321489.5 dated 5 December 2013)

December 4, 2014

Applicant:  Chemical & Biopharmaceutical Laboratories of Patras SA

Short Title:  Proinsulin Derivatives

Inventors:  Dimitrios Gatos, Alexandra Anastasiou and Kleomenis Barlos

Applicant:  Chemical & Biopharmaceutical Laboratories of Patras SA

Short Title:  A PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE (GLP-1 Peptides)

Inventors:  Dimitrios Gatos, Kleomenis Barlos and Konstantinos Barlos